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Fig. 6 | Journal of Experimental & Clinical Cancer Research

Fig. 6

From: Inhibition of retinoic acid receptor α phosphorylation represses the progression of triple-negative breast cancer via transactivating miR-3074-5p to target DHRS3

Fig. 6

RARαS77A suppresses TNBC cell growth in vivo. a-c MDA-MB-231 cells stably transfected with RARαS77A, RARα or vector were injected subcutaneously into BALB/c nu/nu mice. The tumor volume and body weight were measured every 3 days. After 26 days, the mice were sacrificed and the tumors were weighed. d Tumor tissue homogenate was taken for western blotting to detect RARα (p-Ser77) and RARα protein expression. e-f TUNEL staining and IHC analysis of tumor xenografts

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