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Fig. 1 | Journal of Experimental & Clinical Cancer Research

Fig. 1

From: KLF5-induced BBOX1-AS1 contributes to cell malignant phenotypes in non-small cell lung cancer via sponging miR-27a-5p to up-regulate MELK and activate FAK signaling pathway

Fig. 1

BBOX1-AS1 is up-regulated and predicts an inferior prognosis in NSCLC. a and b Heatmap of differentially expressed lncRNAs in lung cancer based on microarray datasets (GSE18842 and GSE19188). c Venn diagram displaying seven up-regulated lncRNA in NSCLC in both GSE18842 and GSE19188. d Expression of BBOX1-AS1 in LUAD and LUSC based on starBase Pan-Cancer Analysis Platform. e The correlation between BBOX1-AS1 expression and prognosis of NSCLC patients was evaculated by the Kaplan-Meier plotter database. f qRT-PCR analysis of BBOX1-AS1 expression in tumor tissues and corresponding non-cancerous tissues from a cohort of 76 ESCC patients. g Kaplan-Meier survival curve was used to examine the overall survival of NSCLC patients with high/low expression of BBOX1-AS1. h BBOX1-AS1 expression was measured by qRT-PCR in bronchial epithelial cell line BEAS-2B and four NSCLC cells. **P < 0.01, ***P < 0.001

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