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Fig. 7 | Journal of Experimental & Clinical Cancer Research

Fig. 7

From: KLF5-induced BBOX1-AS1 contributes to cell malignant phenotypes in non-small cell lung cancer via sponging miR-27a-5p to up-regulate MELK and activate FAK signaling pathway

Fig. 7

BBOX1-AS1 facilitates the malignant progression of NSCLC by regulating MELK expression. a-e A549 and SK-MES-1 cells were transfected with si-NC, si-BBOX1-AS1#2 or si-BBOX1-AS1#2 + MELK. a CCK-8 assays were used to determine cell viability. b Colony formation assays in transfected cells. c Wound healing assays were performed to measure cell migration capability. d Transwell assays were utilized to detect cell invasion ability. e Western blot assays were conducted to exaine the protein levels of E-cadherin, N-cadherin and vimentin. **P < 0.01, ***P < 0.001

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Journal of Experimental & Clinical Cancer Research

ISSN: 1756-9966

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