HSP90-dependent PUS7 overexpression facilitates the metastasis of colorectal cancer cells by regulating LASP1 abundance

Table 1 Correlation between the HSP90/PUS7/LASP1 expression and clinicopathological characteristics in human CRC tissues

Variables	Cases (No.) (n = 93)	HSP90		P	PUS7		P	LASP1		P
Variables	Cases (No.) (n = 93)	Low expression	High expression	P	Low expression	High expression	P	Low expression	High expression	P
Age (years)				0.562			0.780			0.210
< 60	34	9	25		16	18		16	18
≥ 60	59	19	40		26	33		20	39
Gender				0.128			0.533			0.218
Male	52	19	33		22	30		23	29
Female	41	9	32		20	21		13	28
Pathological stage				0.044			0.157			0.836
Stage I	2	2	0		2	0		1	1
Stage II	73	23	50		30	43		29	44
Stage III	18	3	15		10	8		6	12
Tumor size				0.528			0.499			0.042
< 5 cm	48	16	32		23	25		23	25
≥ 5 cm	44	12	32		18	26		12	32
T stage				0.034			0.030			0.005
T2	5	3	2		4	1		5	0
T3	64	21	43		30	34		24	40
T4	16	1	15		3	13		3	13
N stage				0.032			0.249			0.093
N0	51	21	30		22	29		24	27
N1	28	7	21		15	13		7	21
N2	9	0	9		2	7		2	7
Metastasis				0.18			0.408			0.104
0(no)	89	28	61		41	48		36	53
1(yes)	4	0	4		1	3		0	4
Clinical stage				0.034			0.547			0.008
Stage I	4	3	1		3	1		4	0
Stage II	41	16	25		18	23		18	23
Stage III	35	7	28		16	19		9	26
Stage IV	4	0	4		1	3		0	4

ISSN: 1756-9966