Fig. 3
From: N6-methyladenosine-dependent signalling in cancer progression and insights into cancer therapies
N6-methyladenosine and cell apoptosis associated signaling pathway. N6-methyladenosine can get involved in three key apoptosis associated signaling pathways as follows-. a In the mitochondrial pathway, m6A modification can affect cell apoptosis by regulating the fate of Bcl-2 and BMF. b In endoplasmic reticulum pathway, m6A modification can affect cell apoptosis by regulating SEC62. c In death receptor pathway, m6A modification can influences cell apoptosis by regulating TNFRSF2