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Table 1 Clinical-pathologic characteristic of 70 patients with SACC, and the association between DEC2 expression and these variables

From: Inhibition of DEC2 is necessary for exiting cell dormancy in salivary adenoid cystic carcinoma

Clinical-pathologic variables

DEC2 (nuclear)

 

No. of patients

Negative

Positive

P

Age (years)

≤55

34

25

9

0.684

>55

36

28

8

 

Gender

Male

31

23

8

0.795

Female

39

30

9

 

Tumor site

Major salivary gland

21

18

3

0.043

Minor salivary gland

49

30

9

8

T stage

T1/T2

25

16

9

0.091

T3/T4

45

37

8

 

Histological subtype

Cribriform/Tubular

58

38

20

0.009

Solid

12

3

9

 

Recurrence

With

33

20

13

0.005

Without

37

33

4

 

metastasis

With

31

18

13

0.002

Without

39

35

4

 
  1. Immunohistochemistry results showed that the nuclear staining of DEC2 was detected in 17 of 70 and it was significantly associated with tumor site, histological subtype, recurrence and metastasis. Neither was related to age, gender or T stage
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Journal of Experimental & Clinical Cancer Research

ISSN: 1756-9966

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