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Fig. 7 | Journal of Experimental & Clinical Cancer Research

Fig. 7

From: The lnc-CTSLP8 upregulates CTSL1 as a competitive endogenous RNA and promotes ovarian cancer metastasis

Fig. 7

CTSL1 was upregulated in ovarian cancer. a Single-cell RNA sequencing (scRNA-seq) analysis of ovarian cancer. The heatmap shows cell marker (EPCAM for epithelial cells, CD14 for monocytes/macrophages, CD4 for CD4+ T cells) expression patterns in CTSL1+ cells. b scRNA-seq in EPCAM+ cells from three ovarian cancer para-tumor tissues (used as control), ovarian cancer tissue, and the matched peritoneal metastasis tissues. c Quantification of CTSL1 expression in EPCAM+ cells from benign ovarian cyst, ovarian cancer, and peritoneal metastasis tissues with different CTSL1 staining. e and f Quantification of CTSL1 IHC score in different tissues. g Overall survival of ovarian cancer patients with low/high CTSL1 IHC score. h Immunoblotting of CTSL1 in different tissues. i ELISA of CTSL1 in serum and ascites of ovarian cancer patients

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