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Fig. 9 | Journal of Experimental & Clinical Cancer Research

Fig. 9

From: The lnc-CTSLP8 upregulates CTSL1 as a competitive endogenous RNA and promotes ovarian cancer metastasis

Fig. 9

CTSL1 inhibitor and miR-199a-5p abrogated the lnc-CTSLP8-mediated promotion of EMT and autophagy in ovarian cancer. a TEM of the AU, AL, and MT in SKOV3-CTSLP8-OE cells treated with CTSL1 inhibitor Z-FY-DMK, DMSO (negative control), or untreated (blank control). b TEM of the AU, AL, and MT in SKOV3-CTSLP8-OE cells treated with miR-199a-5p or miR-NC (negative control). c and e Immunoblotting of autophagy-related genes and EMT markers in different cell lines. d and f Quantification of relative p62 expression, LC3-II/ LC3-I ratio, and EMT marker expression in different cell lines. h and f Immunofluorescence assay of mRFP-GFP-LC3 in different cell lines

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