Fig. 3

Representative immunohistochemistry images of RCC patient tumour sections and adjacent normal kidney tissues stained with E-cadherin and N-cadherin. Immunohistochemistry was performed as described in Fig. 2. E-cadherin (Cell Signaling; 14,472), images show adjacent normal kidney tissue to be slightly positively stained in the tubules while RCC tissue is negative for any staining. N cadherin (Cell Signaling; 13,116): increase in the membranous expression of N-cadherin in the RCC tumour compared to normal adjacent kidney tissue. Magnification: 40X, Scale bar: 75 μm. Representative images of n = 5 tissues for each antibody