Fig. 2

miR-455-5p suppressed CXCL12 signaling via targeting CXCL12. a Complementary binding sites between CXCL12 3’ UTR and miR-455-5p. b Relative CXCL12 mRNA levels in MTC tissues. c Correlation between miR-455-5p level and CXCL12 mRNA level in MTC tissues. d Relative CXCL12 mRNA level in MTC cells. e Relative CXCL12 mRNA level in mimics NC transfected or miR-455-5p mimics transfected MTC cells. f & g Relative CXCL12 protein level in mimics NC transfected or miR-455-5p mimics transfected MTC cells. h Relative luciferase activity in transfected MTC cells. *P < 0.05; ** P < 0.01; *** P < 0.001