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Fig. 5 | Journal of Experimental & Clinical Cancer Research

Fig. 5

From: circPVT1 regulates medullary thyroid cancer growth and metastasis by targeting miR-455-5p to activate CXCL12/CXCR4 signaling

Fig. 5

Knockdown of circPVT1 suppressed MTC cell proliferation, migration, and invasion. a & b The number of colonies formed in shNC transfected or shcircPVT1 transfected MTC cells. c Flow cytometry analysis of the number of transfected cells in G1, S, and G2 phases. d Flow cytometry analysis of cell apoptosis in MTC cells transfected with shNC or shcircPVT1. e & f Transwell assay and scratch wound healing assay to analyze migration and invasion abilities of transfected cells. g & h EMT-related protein levels in MTC cells transfected with shNC or shcircPVT1. * P < 0.05; ** P < 0.01; *** P < 0.001

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