Fig. 2

HCC-exo promote migration, invasion and EMT via inducing M2 macrophage polarization in HCC. a. Transwell assay tested the invasion and migration of SMMC-7721 cells after co-culture with HCC-exo-treated macrophages; b. Transwell assay tested the invasion and migration of HepG2 cells after co-culture with HCC-exo-treated macrophages; c. RT-qPCR analysis of E-cadherin, N-cadherin, vimentin and MMP7 mRNA expression in SMMC-7721 and HepG2 cells after co-culture with HCC-exo-treated macrophages; data were expressed as mean ± standard deviation (repetition = 3) and evaluated by One-way AVONA and Tukey’s test. * P < 0.05 compared with the SMMC-7721 + M group; ^ P < 0.05 compared with the HepG2 + M group