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Table 2 Univariate and Multivariate Analyses of Factors Associated with Overall Survival

From: CircPVT1 promotes proliferation of lung squamous cell carcinoma by binding to miR-30d/e

Facrors

OS

Univariate

Multivariate

  

p

HR

95%CI

P value

Sex (Female vs. Male)

0.841

  

NA

Age (years)(< 60 vs. ≥60)

0.045

  

NA

Smoking history (Yes vs. No)

0.518

  

NA

TNM stage(I-II vs. III-IV)

0.002

1.940

0.798–4.713

O.143

Tumor size(≤5 cm vs. > 5 cm)

0.000

1.927

0.882–4.207

0.100

Lymph node metastasis (Yes vs. No)

0.007

I.097

0.499–2.410

0.819

Differentiation (Not poor vs. Poor)

0.001

1.367

0.759–2.462

0.297

CircPVT1 expression (High vs. Low)

0.000

2.019

1.118–3.644

0.020

  1. OS Overall survival, NA Not adopted, 95%CI 95% confidence interval, HR Hazard ratio; Cox proportional hazards regression model