Fig. 1

Characterization of exosomes derived from LUAD cells. a Expression of HIF-1α in A549 and H1299 cells under hypoxic and normoxic conditions. b Representative TEM picture of exosomes derived from LUAD cells. c NTA were detected the concentration and size distribution of HExo. d Comparison of exosomes concentration between HExo and NExo. e Western blot analysis for presence of exosomes markers, CD63, TSG101, Flotillin and absence of negative control, Calnexin. Data are presented as the mean ± SD of three independent experiments (**, P<0.01)