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Fig. 2 | Journal of Experimental & Clinical Cancer Research

Fig. 2

From: Loss of RANBP3L leads to transformation of renal epithelial cells towards a renal clear cell carcinoma like phenotype

Fig. 2

Loss of RANBP3L induces morphological changes in mpKCCD cells. A Staining of the F-actin with Alexa-568 coupled phalloidin in Scr, R1 and R3 mpkCCD cells, staining of nucleus with DAPI (Scale bar: 10 μm). White arrows indicate lamelopodia boundary. B Fold change of area covered by lamelopodia of Scr cells compared to RANBP3L-deficient cells. Area covered by lamelopodia was measured with the Zen-blue software. For each condition 2–4 cells from 3 independent biological replicates were measured (n = 3). Values represent mean ± SEM (error bars). n.s., p > 0.05, *, p < 0.05, ***, p < 0,001, 1-way ANOVA

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