Skip to main content
Fig. 2 | Journal of Experimental & Clinical Cancer Research

Fig. 2

From: Targeting WD repeat domain 5 enhances chemosensitivity and inhibits proliferation and programmed death-ligand 1 expression in bladder cancer

Fig. 2

OICR-9429 inhibits bladder cancer cell proliferation by regulating the cell cycle. a. Cell viability was evaluated in T24, UM-UC-3, and TCCSUP BCa cells treated with OICR-9429 or DMSO for 5 days. b. The images and quantification of colony formation assays in three BCa cells treated with two OICR-9429 doses or DMSO. c. Representative images and quantification of the cell cycle in three BCa cells treated with OICR-9429 or DMSO for 48 h. The percentages (%) of cell populations at different stages of the cell cycle are listed in the panels. d. EdU assay measurement of the cell population in S phase and a histogram analysis of EdU-positive cell counts are shown. Blue indicates the nucleus; red indicates S-phase cells. Scale bars, 50 μm (white). *p < 0.05 and **p < 0.01

Back to article page