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Table 1 Members of the PARP family

From: PARP inhibitors in gastric cancer: beacon of hope

Subfamily Family members alternative names catalytic activities
DNA-dependent PARPs PARP1 ARTD1 Poly
PARP2 ARTD2 Poly
PARP3 ARTD3 Mono
Tankyrases PARP5a ARTD5/tankyrase1 Poly
PARP5b ARTD6/tankyrase1 Poly
(CCCH) Zn finger/WWE PARP7 ARTD14/TiPARP Mono
PARP12 ARTD12/ZC3HDC1 Mono
PARP13 ARTD13/ZAP Inactive
Marco PARP9 ARTD9/BAL1 Mono
PARP14 ARTD8/BAL2 Mono
PARP15 ARTD7/BAL3 Mono
Unclassified PARP4 ARTD4/vPARP Mono
PARP6 ARTD17 Mono
PARP8 ARTD16 NA
PARP10 ARTD10 Mono
PARP11 ARTD11 Mono
PARP16 ARTD15 Mono