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Fig. 5 | Journal of Experimental & Clinical Cancer Research

Fig. 5

From: USP1-dependent RPS16 protein stability drives growth and metastasis of human hepatocellular carcinoma cells

Fig. 5

Inhibition of USP1 suppresses migration of HCC cells. a and b Transwell migration assay was performed in HepG2 and HCCLM3 cells treated with ML323, and cells stably expressing USP1 shRNAs or control shRNAs for 72 h. Representative images are shown. Scale bars, 50 μm. c and d Cell migration rate was calculated and quantified from three independent repeats. and f Western blotting analysis was performed in HepG2 and HCCLM3 cells exposed to ML323 for 48 h, and HCC cells stably expressing USP1 shRNAs or control shRNAs using indicated antibodies. Relative intensities of the bands are shown

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