Fig. 7
Knockdown of USP1 reduces growth of HCC in vivo. HepG2 cells stably expressing USP1 shRNAs or control shRNAs were transplanted in nude mice for 27 days. a Images of HepG2 xenografts in each group are shown. b Tumor weight, c Tumor size, and d body weight of nude mice is shown. e Expressions of RPS16 and Ki67 in tumor tissues were determined by immunohistochemistry assay. Scale bar, 50 μm. f Relative intensities of RPS16 and Ki67 were calculated and quantified using an Image J software