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Fig. 6 | Journal of Experimental & Clinical Cancer Research

Fig. 6

From: Long non-coding RNA DLEU2 drives EMT and glycolysis in endometrial cancer through HK2 by competitively binding with miR-455 and by modulating the EZH2/miR-181a pathway

Fig. 6

Aberrant expression of DLEU2 drives EMT and glycolysis in EC. a Morphological changes upon functional overexpression or inhibition of DLEU2. b Western blotting analysis of the indicated proteins in EC cells following overexpression or knockdown of DLEU2. c, d, e Cell migration (c), invasion (d), sphere formation (e) of EC cells upon overexpression or inhibition of DLEU2. f Cell glucose consumption and lactate production of Ishikawa cells following overexpression of HK2. g Cell viability assay to assess the effects of DLEU2 knockdown on the cellular response to TX. Ishi: Ishikawa; vec: vector; sh: shRNA. *P < 0.05

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