Fig. 5

The relationship between tiRNA-Gly and RBM17 is proved. A RBM17 expression in higher tiRNA-Gly expression group (tiRNA-Gly^High, n = 68) is higher than that in lower tiRNA-Gly expression group (tiRNA-Gly^Low, n = 23) by IHC. Scale bar = 20 μm. B-C Rescue experiments show that tiRNA-Gly effect in CCK-8 assay and migration assay is partly compromised by RBM17 knockdown in TPC-1 and BCPAP cells. Scale bar = 100 μm. D RBM17 expression is downregulated in si-tiRNA-Gly group (S1–10) compared with normal saline group (NS, N1–10) in mice subcutaneous tumors by western blot and its quantification results. β-actin referred as a control. Values are triple replicated and displayed in mean ± SD. *p < 0.05, **p < 0.01, ***p < 0.001