Fig. 10

NRF2 expression in RCC tumor tissues versus in the associated normal tissues: Boxplots of the NRF2 expression level across TCGA-RCC subtypes in renal tumor (red) versus the associated normal renal tissues (blue) were presented (A). NRF2 expression among different stages of chRCC (B), ccRCC (C) and pRCC (D) versus the associated normal renal tissues was box-plotted. NRF2 expression was presented in the log2 (TPM + 1) scale format. Data were presented as the mean ± SD. A t-test was used to evaluate the statistical significance of the NRF2 mRNA expression level in normal renal tissues versus tumor tissues. One-way ANOVA was used to compare NRF2 expression among normal renal tissues versus different stages of RCC tumor tissues. The figure was performed using R version 4.0.3