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Fig. 3 | Journal of Experimental & Clinical Cancer Research

Fig. 3

From: Kidney cancer biomarkers and targets for therapeutics: survivin (BIRC5), XIAP, MCL-1, HIF1α, HIF2α, NRF2, MDM2, MDM4, p53, KRAS and AKT in renal cell carcinoma

Fig. 3

XIAP expression in RCC tumor tissues versus in the associated normal tissues: Boxplots of the XIAP expression level across TCGA-RCC subtypes in renal tumor (red) versus the associated normal renal tissues (blue) were presented (A). BIRC5/survivin expression among different stages of chRCC (B), ccRCC (C) and pRCC (D) versus the associated normal tissues was box-plotted. XIAP expression was presented in the log2 (TPM + 1) scale format. Data were presented as the mean ± SD. A t-test was used to evaluate the statistical significance of the XIAP mRNA expression level in normal renal tissues versus tumor tissues. One-way ANOVA was used to compare XIAP expression among normal renal tissues versus different stages of RCC tumor tissues. The figure was performed using R version 4.0.3

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