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Fig. 5 | Journal of Experimental & Clinical Cancer Research

Fig. 5

From: Kidney cancer biomarkers and targets for therapeutics: survivin (BIRC5), XIAP, MCL-1, HIF1α, HIF2α, NRF2, MDM2, MDM4, p53, KRAS and AKT in renal cell carcinoma

Fig. 5

MCL-1 expression in RCC tumor tissues versus in the associate normal tissues: Boxplots of the MCL-1 expression level across TCGA-RCC subtypes in renal tumor (red) versus the associated normal renal tissues (blue) were presented (A). MCL-1 expression among different stages of chRCC (B), ccRCC (C) and pRCC (D) versus the associated normal tissues was box-plotted. MCL-1 expression was presented in the log2 (TPM + 1) scale format. Data were presented as the mean ± SD. A t-test was used to evaluate the statistical significance of the mRNA expression level in normal renal tissues versus tumor tissues. One-way ANOVA was used to compare MCL-1 expression among normal renal tissues versus different stages of RCC tumor tissues. The figure was performed using R version 4.0.3

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