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Fig. 2 | Journal of Experimental & Clinical Cancer Research

Fig. 2

From: Circular RNA circ_001422 promotes the progression and metastasis of osteosarcoma via the miR-195-5p/FGF2/PI3K/Akt axis

Fig. 2

Correlation of circ_001422 expression with clinical characteristics. a. The relative quantification (RQ) value of circ_001422 was determined by qRT-PCR in 55 paired OS tissues and adjacent noncancerous tissues. b. Fold changes (log2) in circ_001422 expression in each paired sample, arranged in descending order. c. Correlation between circ_001422 expression and clinical stage. d. Correlation between circ_001422 expression and tumor size. e. Correlation between circ_001422 expression and distant metastasis. f. Correlation between circ_001422 expression and primary tumor location. g. Patients with OS were divided into two groups according to the median level of circ_001422 expression. Overall survival was analyzed by the Kaplan-Meier method with the log-rank test. h. ROC curve showing the diagnostic sensitivity and specificity of circ_001422 for OS. n.s., not significant; *P < 0.05; **P < 0.01; ***P < 0.001

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