Skip to main content
Fig. 5 | Journal of Experimental & Clinical Cancer Research

Fig. 5

From: Elesclomol-induced increase of mitochondrial reactive oxygen species impairs glioblastoma stem-like cell survival and tumor growth

Fig. 5

Elesclomol and TMZ combination is significantly more effective than TMZ alone. Cell viability assay performed on all the four selected GSC lines either in stem cell medium (A) or in endothelial conditions (B), treated with elesclomol alone, TMZ alone, and combined elesclomol and TMZ. Results obtained from three independent experiments are shown as percentage vs control untreated cells and reported as means ± SD. * p < 0.05; ** p < 0.01; *** p < 0.001 vs TMZ or eleclomol (Student-t test). The calculated excess over the predicted Bliss additivism model is shown in the tables on the right

Back to article page