Skip to main content

Table 1 Lifespan increase in different cellular models cultured under different oxygen concentrations

From: Cellular senescence or stemness: hypoxia flips the coin

Cellular model

O2 concentration

Lifespan increase

Reference

IMR90, WI38

2 and 10%

25%

Packer et al. Nature, 1977

IMR90

1, 6 and 12%

22%

Saito et al. Exp. Cell Research, 1995

Mouse embryonal fibroblasts (MEFs)

3%

500%

Parrinello et al. Nature Cell Biology, 2003

Bovine embryonal fibroblasts (BFF)

2%

80%

Betts et al. Biogerontology, 2008