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Fig. 1 | Journal of Experimental & Clinical Cancer Research

Fig. 1

From: XPO1/CRM1 is a promising prognostic indicator for neuroblastoma and represented a therapeutic target by selective inhibitor verdinexor

Fig. 1

Overexpression of XPO1 is associated with poor clinical characteristics and prognosis of neuroblastoma patients. AXPO1 mRNA is overexpressed in patients with age at diagnosis more than 18 months and B advanced INSS stage. C Patients with high XPO1 mRNA expression present shorter overall survival time. D panoramic view of TMA. E XPO1 protein is overexpressed in patients with age at diagnosis more than 18 months and F advanced INSS stage. G Patients with high XPO1 protein expression present shorter overall survival time. TMA, specimens and tissue microarray. INSS, International Neuroblastoma Staging System. ** P < 0.01, *** P < 0.001

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