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Fig. 2 | Journal of Experimental & Clinical Cancer Research

Fig. 2

From: A review of Dynamin 2 involvement in cancers highlights a promising therapeutic target

Fig. 2

DNM2-dependent processes in tumor cells. AHI-1: Abelson helper integration site-1. BCR-ABL: product of the BCR-ABL fusion gene. Cort: Cortactin. DNM2: Dynamin 2. FasL: Fas Ligand. FBP17: Formin Binding Protein 17. HIF1: hypoxia-induced factor 1. IL-7: interleukin 7. IL-24: interleukin 24. MAPK: mitogen-activated protein kinase. MT1-MMP: membrane type 1 matrix metalloproteinase. P: phosphorylated residue in DNM2. PRL: prolactin. ROS: reactive oxygen species. SFK: Src-family kinase. SHP2: tyrosine-protein phosphatase non-receptor type 11. STAT3: signal transducer and activator of transcription 3. The miR199a and miR638 are both produced from the DNM2 gene. The figure was built using the Servier medical art database

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