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Table 1 Characteristics of the 50 study participants (Σ = 56 samples)

From: Establishment and characterization of patient-derived head and neck cancer models from surgical specimens and endoscopic biopsies

Group characteristics Surgery
Σ n = 26
Biopsy
Σ n = 28
  % n % n
Female 15 4 18 5
Male 85 22 82 23
Age [years] 64.8  ± 9.4 64.5  ± 8.1
Performance status [ECOG] 1.0  ± 0.7 1.1  ± 1.0
Noxae
 Smoking [> 10 py] 73 19 68 19
 Alcohol [> 1 drink/d] 58 15 32 9
Localization 38 10   
 Oral cavity 23 6 25 7
 Oropharnyx 12 3 46 13
 Hypopharynx 27 7 7 2
 Larynx    18 5
 CUP    4 1
p16 status
 Positive 15 4 32 9
 Negative 85 22 68 19
G1/G2/G3 [%] 6/73/21 5/70/25
T1/T2/T3/T4 [%] 13/27/30/30 -/17/29/54*
N0/N1/N2/N3 [%] 56/30/5/9 15/35/60/0*
  1. Values depict absolute/relative numbers and mean ± SD. Chi-square test was performed to analyze homogeneity of surgery vs. biopsy groups (*p < 0.05)
  2. Abbreviations: py pack years, CUP cancer of unknown primary, G1/2/3 grading