Fig. 1

EMX1 and EMX2 expression correlated with effectors of the Wnt pathway in samples from sarcoma patients. A, D, G, J, and M Bar charts showing the classification of EMX1 and EMX2 target genes by KEGG analysis in sarcoma patient databases. The Y-axis represents the KEGG pathways related to the regulatory pathways of stem cells with a p-value < 0.05. B, E, H, K and N, Venn diagrams of the regulatory genes of the Wnt pathway correlated with EMX1 and EMX2. P and Q Venn diagrams encompassing all analyzed sarcoma datasets with respect to EMX1 and EMX2 correlations. C, F, I, L and O Relative expression of the positive prominent effectors WNT1, CTNNB1, MYC and CCND1 and the negative effectors AXIN1 and GSK3-β