Fig. 6

COX-2 and E2 expression by IHC in archival malignant pleural mesothelioma tumor specimens. A, Representative IHC of COX-2 and E2 in MPM and their relative immunoreactivity score (IRS). The scale bar is 30 μm. B, Graph shows the number of MPM samples with E2 and COX-2 moderate and mild IRS by IHC. C, graphical representation of Spearman’s correlation between COX-2 and CYP19A1 IRS value in MPM specimens