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Table 1 Characteristics of the different types of EOC

From: The Anterior GRadient (AGR) family proteins in epithelial ovarian cancer

  Type 1 Type 2
Anatomopathological subtype Low grade serous
Endometrioid
Clear cells
Mucinous tumour
High grade serous
Carcinosarcoma
Undifferentiated
Severity 10% of deaths 90% of deaths
Mutations ERRB2, KRAS, BRAF pathway, MMR, ARID1A, PTEN, PI3K P53, homologous recombination defects
Precursors Borderline tumours, endometriosis Serous Tubal In situ Carcinoma