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Table 1 Characteristics of the different types of EOC

From: The Anterior GRadient (AGR) family proteins in epithelial ovarian cancer

 

Type 1

Type 2

Anatomopathological subtype

Low grade serous

Endometrioid

Clear cells

Mucinous tumour

High grade serous

Carcinosarcoma

Undifferentiated

Severity

10% of deaths

90% of deaths

Mutations

ERRB2, KRAS, BRAF pathway, MMR, ARID1A, PTEN, PI3K

P53, homologous recombination defects

Precursors

Borderline tumours, endometriosis

Serous Tubal In situ Carcinoma