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Fig. 3 | Journal of Experimental & Clinical Cancer Research

Fig. 3

From: Apatinib triggers autophagic and apoptotic cell death via VEGFR2/STAT3/PD-L1 and ROS/Nrf2/p62 signaling in lung cancer

Fig. 3

Apatinib inhibited malignant growth and cancer stem cell-like properties in NSCLC cells. a Plate colony formation of A549 and H1299 cells after apatinib treatment for 14 days and quantitation of colony numbers. The data are presented as mean ± SD (n = 3). **p < 0.01 vs. control. b Soft agar colony formation of A549 and H1299 cells after apatinib treatment for 14 days and quantitation of colony numbers. Scar bar = 200 μm. The data are presented as mean ± SD (n = 3). **p < 0.01 vs. control. c Flow cytometry analysis of CD133-positive cells and quantification of the percentage of CD133-positive cells. The data are presented as mean ± SD (n = 3). **p < 0.01 vs. control

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