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Fig. 4 | Journal of Experimental & Clinical Cancer Research

Fig. 4

From: Neuromedin U induces an invasive phenotype in CRC cells expressing the NMUR2 receptor

Fig. 4

NMU receptor expression in normal epithelial and colorectal cancer cells. A NMUR1 and B NMUR2  mRNA levels were analysed in cancer cells and compared to those in normal epithelial cells (*p ≤ 0.05, ***p ≤ 0.001, ****p ≤ 0.0001; n ≥ 6). C NMUR1 and D NMUR2 expression levels were analysed in cells treated with 50 µM 5-aza-CdR inhibitor (INH) for 4 days. GAPDH or β-actin was used as the internal control (*p ≤ 0.05, ***p ≤ 0.001; n ≥ 4). The results are shown as the medians with interquartile ranges. The images show representative results of electrophoretic analysis of real-time PCR products. E NTSR1 and F GHSR1b mRNA levels were analysed in cancer cells and compared to those in normal epithelial cells. GAPDH or β-actin was used as the internal control. The results are shown as the median with interquartile range (*p ≤ 0.05, **p ≤ 0.01; n ≥ 4)

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