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Fig. 6 | Journal of Experimental & Clinical Cancer Research

Fig. 6

From: Circ-GALNT16 restrains colorectal cancer progression by enhancing the SUMOylation of hnRNPK

Fig. 6

Serpine1 is downregulated by circ-GALNT16 and has a connection with CRC progression. a, b. Heatmap and scatter diagram showed the RNA-seq result in circ-GALNT16 overexpression and control RKO cells. c. Several candidates were validated by qRT-PCR. d, e. The mRNA and protein levels of Serpine1 in circ-GALNT16 knockdown and overexpression cells. f. Correlation analysis between circ-GALNT16 and Serpine1. (R = -0.3106, P = 0.0125) g-j. Serpine1 expression in CRC and the correlation with relative clinical features analysis from TCGA. All data are presented as the means ± SD of three independent experiments. nsp > 0.05, *p < 0.05, **p < 0.01, ***p < 0.001

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