Fig. 6
From: Cyclin G2 reverses immunosuppressive tumor microenvironment and potentiates PD-1 blockade in glioma
Cyclin G2 negatively correlated with tumor-infiltrating Tregs in glioma. a Representative immunohistochemical staining images for cyclin G2 and Foxp3 in glioma specimens. Magnification, 200×, 400×. b Foxp3 positive staining in patients with low cyclin G2 expression and high cyclin G2 expression (n = 40 per group). Data are presented as the mean ± s.d. ***p < 0.001. c A schematic model depicting the functions of cyclin G2 in the TME of glioma