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Fig. 6 | Journal of Experimental & Clinical Cancer Research

Fig. 6

From: SHOX2 cooperates with STAT3 to promote breast cancer metastasis through the transcriptional activation of WASF3

Fig. 6

WASF3 is critical for SHOX2-mediated breast cancer cell invasion. (a, b) The effect of WASF3 gene manipulations on cell invasion in SHOX2 overexpressing T47D cells and knockdown MDA-MB-231 cells. Quantitative data of (a) are shown in (b). (c) The effect of WASF3 knockdown on EMT induced by SHOX2 overexpression in T47D cells. (d) The effect of WASF3 gene manipulations on E-cadherin levels in SHOX2 overexpressing T47D cells and SHOX2 knockdown MDA-MB-231 cells. *p < 0.05, **p < 0.01

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