Fig. 7
LNCAROD plays a more important role in mediating HCC tumorigenesis under hypoxia than normoxia. A CCK-8 cell viability, B colony formation, C migration and invasion, D glucose consumption, E lactate production, F ATP production, G ECAR, H PKM2 mRNA expression, and I PKM2 protein expression assays in SMMC-7721 and Huh7 cells transfected with the vector or LNCAROD under normoxia (20 % O2) or hypoxia (1 % O2 or in the presence of CoCl2). Data are shown as the mean ± SD. *P < 0.05; **P < 0.01