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Table 1 Association between IHC score of PFKFB4, clinicopathological parameters and NCOA3 expression (SE = standard error)

From: PFKFB4 is overexpressed in clear-cell renal cell carcinoma promoting pentose phosphate pathway that mediates Sunitinib resistance

Parameter

Breakdown

N

PFKFB4 Expression

P

Median

SE

T

T1-T2

258

1

0.04

<0.001

T3-T4

66

2

0.12

N

N0

274

1

0.04

0.003

N1

50

2

0.14

M

M0

314

1

0.04

<0.001

M1

10

2

0.15

Gender

Male

196

1

0.06

0.547

Female

128

1

0.07

Grade

I-II

262

1

0.04

<0.001

III-IV

62

2

0.12

Neoadjuvant Tx

No

306

1

0.04

0.001

Yes

18

2

0.21

Correlation

 

Median

SE

Spearman r

P

Age

57

0.350

-0.449

<0.001

NCOA3

1

0.040

0.810

<0.001