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Table 1 Association between IHC score of PFKFB4, clinicopathological parameters and NCOA3 expression (SE = standard error)

From: PFKFB4 is overexpressed in clear-cell renal cell carcinoma promoting pentose phosphate pathway that mediates Sunitinib resistance

Parameter Breakdown N PFKFB4 Expression P
Median SE
T T1-T2 258 1 0.04 <0.001
T3-T4 66 2 0.12
N N0 274 1 0.04 0.003
N1 50 2 0.14
M M0 314 1 0.04 <0.001
M1 10 2 0.15
Gender Male 196 1 0.06 0.547
Female 128 1 0.07
Grade I-II 262 1 0.04 <0.001
III-IV 62 2 0.12
Neoadjuvant Tx No 306 1 0.04 0.001
Yes 18 2 0.21
Correlation   Median SE Spearman r P
Age 57 0.350 -0.449 <0.001
NCOA3 1 0.040 0.810 <0.001