Fig. 5

Similarities and differences in morphology and molecular regulations between embryonic implantation to the uterine endometrium and CTC adhesion-invasion to vascular endothelium. A Global summary of similarities and differences between blastocyst implantation and cancer cell adhesion and invasion. B Morphological differences between blastocyst implantation to the uterine endometrium and CTC adhesion-invasion to vascular endothelium (fluorescence microscope). C 17β-estradiol plus progesterone promote, whereas, mifepristone and metapristone inhibit migration and invasion of blastocyst or cancer cells to endometrium or endothelium, respectively, by regulating many cell adhesion molecules involved in the processes