Fig. 6

Effects of E2 (10 nM) plus P4, mifepristone and metapristone on the levels of integrinβ1, α5 and αvβ3 expressed by RL95-2 cells and HUVECs, which were analyzed by flow cytometry, RT-PCR. Flow cytometry (A, B) and RT-PCR (C, D) analyses showed that E2 plus P4 enhanced the expressions of integrinα5 and β1 in RL95-2 cells and HUVECs, whereas, mifepristone and metapristone inhibited the expressions of integrinα5 and β1 in RL95-2 cells analyzed by flow cytometry (E, F) and RT-PCR (G), integrin αvβ3 in HUVECs analyzed by flow cytometry (H) and RT-PCR (I). Each bar represents the mean ± SEM (n = 3); *, P < 0.05; **, P < 0.01, compared with the control