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Table 1 Correlation between MYSM1 expression and clinicopathological features of CRC patients in the tissue microarray of metastasis

From: MYSM1 inhibits human colorectal cancer tumorigenesis by activating miR-200 family members/CDH1 and blocking PI3K/AKT signaling

  Total Low MYSM1 High MYSM1   
Variable N % N % N % χ2 P Valuea
Pathological Diagnosis
 Adjacent Normal Tissue 38 30.7 6 9.5 32 52.5 32.054 < 0.001
 Adenocarcinoma 53 42.7 30 47.6 23 37.7
 Lymph Node Metastasis 33 26.6 27 42.9 6 9.8
 Adjacent Normal Tissue 38 41.8 6 16.7 32 58.2 15.419 < 0.001
 Adenocarcinoma 53 58.2 30 83.3 23 41.8
 Adenocarcinoma 53 61.6 30 52.6 23 79.3 5.785 0.016
 Lymph Node Metastasis 33 38.4 27 47.4 6 20.7
 Adjacent Normal Tissue 38 53.5 6 18.2 32 84.2 30.955 < 0.001
 Lymph Node Metastasis 33 46.5 27 81.8 6 15.8
Location
 Colon 45 84.9 28 93.3 17 73.9 3.831 0.050
 Rectum 8 15.1 2 6.7 6 26.1
Age (y)
  < 40 8 15.1 5 16.7 3 13.0 1.065 0.587
 40–60 28 52.8 14 46.7 14 60.9
  > 60 17 32.1 11 36.6 6 26.1
Gender
 M 38 71.7 21 70.0 17 73.9 0.098 0.754
 F 15 28.3 9 30.0 6 26.1
Grade
 I 10 18.9 8 26.7 2 8.7 2.783 0.249
 II 26 49.1 13 43.3 13 56.5
 III 17 32.0 9 30.0 8 34.8
Stage
  ≤ IIIB 44 83.0 22 73.3 22 95.7 4.600 0.032
  ≥ IIIC 9 17.0 8 26.7 1 4.3
Tumor Stage
  ≤ T3 35 66.0 16 53.3 19 82.6 4.975 0.026
 T4 18 34.0 14 46.7 4 17.4
Nodal Stage
 N0 13 24.5 9 30.0 4 17.4 1.759 0.415
 N1 27 51.0 13 43.3 14 60.9
 N2 13 24.5 8 26.7 5 21.7
  1. aThe P values were calculated in SPSS 25.0 using a chi-square test
  2. P values < 0.05 were considered to indicate statistical significance