Table 1 Correlation between MYSM1 expression and clinicopathological features of CRC patients in the tissue microarray of metastasis

Pathological Diagnosis

 Adjacent Normal Tissue

38

30.7

6

9.5

32

52.5

32.054

< 0.001

 Adenocarcinoma

53

42.7

30

47.6

23

37.7

 Lymph Node Metastasis

33

26.6

27

42.9

6

9.8

 Adjacent Normal Tissue

38

41.8

6

16.7

32

58.2

15.419

< 0.001

 Adenocarcinoma

53

58.2

30

83.3

23

41.8

 Adenocarcinoma

53

61.6

30

52.6

23

79.3

5.785

0.016

 Lymph Node Metastasis

33

38.4

27

47.4

6

20.7

 Adjacent Normal Tissue

38

53.5

6

18.2

32

84.2

30.955

< 0.001

 Lymph Node Metastasis

33

46.5

27

81.8

6

15.8

Location

 Colon

45

84.9

28

93.3

17

73.9

3.831

0.050

 Rectum

8

15.1

2

6.7

6

26.1

Age (y)

  < 40

8

15.1

5

16.7

3

13.0

1.065

0.587

 40–60

28

52.8

14

46.7

14

60.9

  > 60

17

32.1

11

36.6

6

26.1

Gender

 M

38

71.7

21

70.0

17

73.9

0.098

0.754

 F

15

28.3

9

30.0

6

26.1

Grade

 I

10

18.9

8

26.7

2

8.7

2.783

0.249

 II

26

49.1

13

43.3

13

56.5

 III

17

32.0

9

30.0

8

34.8

Stage

  ≤ IIIB

44

83.0

22

73.3

22

95.7

4.600

0.032

  ≥ IIIC

9

17.0

8

26.7

1

4.3

Tumor Stage

  ≤ T₃

35

66.0

16

53.3

19

82.6

4.975

0.026

 T₄

18

34.0

14

46.7

4

17.4

Nodal Stage

 N₀

13

24.5

9

30.0

4

17.4

1.759

0.415

 N₁

27

51.0

13

43.3

14

60.9

 N₂

13

24.5

8

26.7

5

21.7