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Table 1 Relationships between miR-378a-3p expression and clinicopathological characteristics of HCC patients

From: DNMT1-induced miR-378a-3p silencing promotes angiogenesis via the NF-κB signaling pathway by targeting TRAF1 in hepatocellular carcinoma

Clinicopathological characteristics

n

Low expression

High expression

P value

Total

108

54

54

 

Gender

   

0.060

 Male

75

33

42

 

 Female

33

21

12

 

Age (years)

   

0.440

 ≤ 60

83

41

42

 

 > 60

25

13

12

 

Grade of differentiation

   

0.123

 Low

56

32

24

 

 High-Middle

52

22

30

 

Tumor diameter (cm)

   

0.123

 ≤ 5

50

29

21

 

 > 5

58

25

33

 

Liver function (Child-Pugh stage)

   

0.588

 A

92

45

47

 

 B or C

16

9

7

 

Hepatocirrhosis

   

0.288

 Absent

31

13

18

 

 Present

77

41

36

 

HBV infection

   

0.555

 Absent

43

20

23

 

 Present

65

34

31

 

Thrombosis of tumor blood vessel

   

0.011

 Absent

65

26

39

 

 Present

43

28

15

 

AFP (ng/ml)

   

0.083

 ≤ 20

53

22

31

 

 > 20

55

32

23

 

BCLC stage

   

0.552

 A

41

19

22

 

 B, C, or D

67

35

32

 

Envelope

   

0.700

 Absent

52

25

27

 

 Present

56

29

27

 

Tumor satellite

   

0.079

 Absent

63

27

36

 

 Present

45

27

18

 

MVD

   

< 0.001

 High

59

45

14

 

 Low

49

9

40

 
  1. AFP serum alpha fetoprotein, HBV hepatitis B virus, BCLC Barcelona Clinic Liver Cancer