Table 1 Composition of exosomes
Type | Â | Cargoes | Reference |
|---|---|---|---|
Protein | Tetraspanin | CD9, CD63, CD81, etc | |
Heat shock protein | Hsp70, Hsp90, etc | ||
MVB formation | ALIX, TSG101, etc | ||
Membrane transport and fusion proteins | Rab, Annexins (I, II, IV, V, VI), etc | ||
Antigen presentation | MCH I, MCH II, etc | ||
Adhesion molecules | integrins, ICAM-1, CD146, etc | ||
Lipid raft | LAPA, Flotillin-1, Cholesterol, etc | ||
Cytoskeletal proteins | Â | ||
Lipids | Cholesterol, ceramide, phosphatidylserine, phosphatidylinositol, phosphatidylcholine, sphingomyelin, ganglioside, etc | Â | |
Nucleic acids | DNA, mRNA, miRNA, lncRNA, circRNA, etc | Â |