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Table 2 The results of yeast two-hybrid screening assay

From: STOML2 interacts with PHB through activating MAPK signaling pathway to promote colorectal Cancer proliferation

Gene name

Official full name

Ensembl ID

Description

Positive count

PHB

Prohibitin

00000167085

Regulates mitochondrial respiration activity and in aging.

4

FLI1

Fli-1 proto-oncogene, ETS transcription factor

00000151702

Sequence-specific transcriptional activator recognizes the DNA sequence 5′-C [CA]GGAAGT-3′.

4

PHB2

Prohibitin 2

00000215021

Mediator of transcriptional repression by nuclear hormone receptors via recruitment of histone deacetylases.

3

DTYMK

Deoxythymidylate Kinase

00000168393

Catalyzes the conversion of dTMP to dTDP.

3

GLP1R

Glucagon Like Peptide 1 Receptor

00000112164

Signal activation of adenylyl cyclase and increased intracellular cAMP levels.

3

ATP5PD

ATP Synthase Peripheral Stalk Subunit D

00000167863

Proton transmembrane transporter activity.

2

PRSS2

Serine protease 2

00000275896

Expressed in pancreas and involved in defensin processing in ileum.

2

GLP1

Glucagon

00000115263

Regulates glucose metabolism and homeostasis

2

CD8A

T-cell surface glycoprotein CD8 alpha chain isoform 2 precursor

00000153563

Coreceptor for MHC class I molecule: peptide complex In T-cells.

2

CETN1

Centrin 1

00000177143

microtubule-organizing center structure and function

1

ATP5PB

ATP synthase peripheral stalk-membrane subunit b

00000167863

 

1

CPVL

Carboxypeptidase

Vitellogenic Like

00000106066

Digestion of phagocytosed particles in the lysosome, inflammatory protease cascade, and trimming of peptides for antigen presentation.

1

TCF7L2

Transcription Factor 7 Like 2

00000148737

Participates in the Wnt signaling pathway and modulates MYC expression by binding to its promoter in a sequence-specific manner

1