Skip to main content
Fig. 2 | Journal of Experimental & Clinical Cancer Research

Fig. 2

From: Arachidonic acid drives adaptive responses to chemotherapy-induced stress in malignant mesothelioma

Fig. 2

PUFAs were increased by pemetrexed treatment. A. Representative box plots of PUFAs (namely, arachidonate (20:4n6), eicosenoate (20:1n9 or 11) and docosahexaenoate (DHA; 22:6n3) as detected by mass spectrometry in the conditioned media from pem-treated cells. No changes in human untransformed mesothelial cells (HMC) cultures were recorded. B. ELISA-based detection of arachidonic acid (AA) in the conditioned media of the indicated MPM cell line treated with pemetrexed as indicated in Fig. 1A. AA levels were expressed as folds over cell-free media. No increase of AA in the pem-treated HMC or in the immortalized LP9 mesothelial cells was recorded. Statistics: * p < 0.05; ** p < 0.01. ns = not significant (p > 0.05)

Back to article page