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Fig. 3 | Journal of Experimental & Clinical Cancer Research

Fig. 3

From: Arachidonic acid drives adaptive responses to chemotherapy-induced stress in malignant mesothelioma

Fig. 3

cPLA2 mediates the release of AA in pemetrexed-treated cells. A. Histogram showing the relative levels of PLA2G4A mRNA in ctrl- and pem-treated cells, at 24 h, as detected by RT-QPCR. B. cPLA2 activity detected by ELISA assay in the indicated cell lines treated with ctrl- or -pem for 24 h. C. Box plots showing the levels of AA in the indicated mesothelioma cell lines pretreated or not with two cPLA2 inhibitors for 90 min before being challenged with pem. Statistics: * p < 0.05; ** p < 0.01. ns = not significant (p > 0.05)

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