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Fig. 7 | Journal of Experimental & Clinical Cancer Research

Fig. 7

From: Replication catastrophe is responsible for intrinsic PAR glycohydrolase inhibitor-sensitivity in patient-derived ovarian cancer models

Fig. 7

DNA replication gene expression in OCMs does not correlate with PARGi-sensitivity. A Heatmap showing RNAseq of 29 OCMs ranked by sum of Z-scores for 25 DNA replication genes where red = high expression; white = average expression and blue = low expression. B XY plot showing colony formation area and the sum of Z-scores for the expression of 25 DNA replication genes from RNAseq of 29 OCMs. PARGi sensitivity as determined by colony formation assay (see Fig. S6B). Note: RNAseq was unavailable for OCMs 267, 250–2, and 162–2. See also Fig. S6 and S9

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