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Fig. 2 | Journal of Experimental & Clinical Cancer Research

Fig. 2

From: High-dose intravenous vitamin C, a promising multi-targeting agent in the treatment of cancer

Fig. 2

Use of high-dose VitC as adjuvant agent in combination with anti-cancer agents. A Described effect of 59 anti-cancer agents combined with high dose vitC investigated in a total of 71 pre-clinical in vitro and in vivo studies (updated may 2021) describing synergy, enhanced efficacy, superior or equivalent effect, reduced toxicity and/or no benefit. B Number of combinations per treatment type. C Described effect per dose group in vitro and in vivo. D Treatment exposure in vitro in hours and frequency dosage in vivo. E Described solvent used for VitC preparation. Use of water stands for MiliQ water, demi water and sterile water; N/S, not specified

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